Research Area

NEUROBIOLOGY

1) Investigate the cellular and molecular mechanisms underlying chronic itch and possibly pain in mice
2) To characterize the subtype of itch and pain-responsive neurons in the spinal cord
3) Tracing the neural circuit for itch sensation in the spinal cord and CNS
4) Discover the degree to which specific mechanisms of itch are conserved across mammalian species.

The Mishra lab will use a wide range of powerful new tools to address these questions including molecular genetics, deep sequencing, functional imaging, electrophysiology and optogenetics along with pharmacological and behavioral tools.